Patent Information

Application Number
3339/MUM/2010
Patent Number
Invention Field
CHEMICAL
Publication Type
INA
Publication Number
08/2014
Status
Grant Date
Filing Date
Grant Date
Renewal Date

Abstract

Abstract: The present invention comprises preparation of Fenspiride hydrochloride (Ia) starting from N-(2-phenylethyl)-2-oxo-6-azaspiro[2.5]octane (III) by a novel method. The compound of formula (III) is converted to 4-(aminomethyl)-1-(2-phenyIethyl)piperidin-4-ol of formula (VI) either by treatment with sodium azide/ammonium chloride followed by reduction or by treating with potassium phthalimide/phthalimide followed by reaction with hydrazine hydrate to give compound of formula (VI) which is then converted to Fenspiride free base (I) of desired purity and impurity profile by subsequent treatment with carbonyl diimidazole.

Applicants

1. EMCURE PHARMACEUTICAL LIMITED
EMCURE HOUSE, T-184, M.I,D.C., BHOSARI, PUNE-411 026, INDIA.

Inventors

1. GURJAR MUKUND KESHAV
EMCURE PHARMACEUTICAL LIMITED EMCURE HOUSE, T-184, M.I,D.C., BHOSARI, PUNE-411 026, INDIA
2. MAIKAP GOLAKCHANDRA SUDARSHAN
EMCURE PHARMACEUTICAL LIMITED EMCURE HOUSE, T-184, M.I,D.C.,BHOSARI, PUNE-411 026, INDIA.
3. MAHAJAN ULHAS SUPADU
EMCURE PHARMACEUTICAL LIMITED EMCURE HOUSE, T-184, M.I,D.C.,BHOSARI, PUNE-411 026, INDIA.
4. DESHPANDE SHAILESH SITARAM
EMCURE PHARMACEUTICAL LIMITED EMCURE HOUSE, T-184, M.I,D.C.,BHOSARI, PUNE-411 026, INDIA.
5. PATIL DEVIDAS BARKU
EMCURE PHARMACEUTICAL LIMITED EMCURE HOUSE, T-184, M.I,D.C.,BHOSARI, PUNE-411 026, INDIA.
6. MEHTA SAMIT SATISH
EMCURE PHARMACEUTICAL LIMITED EMCURE HOUSE, T-184, M.I,D.C.,BHOSARI, PUNE-411 026, INDIA.

Specification

1. GURJAR MUKUND KESHAV
EMCURE PHARMACEUTICAL LIMITED EMCURE HOUSE, T-184, M.I,D.C., BHOSARI, PUNE-411 026, INDIA
2. MAIKAP GOLAKCHANDRA SUDARSHAN
EMCURE PHARMACEUTICAL LIMITED EMCURE HOUSE, T-184, M.I,D.C.,BHOSARI, PUNE-411 026, INDIA.
3. MAHAJAN ULHAS SUPADU
EMCURE PHARMACEUTICAL LIMITED EMCURE HOUSE, T-184, M.I,D.C.,BHOSARI, PUNE-411 026, INDIA.
4. DESHPANDE SHAILESH SITARAM
EMCURE PHARMACEUTICAL LIMITED EMCURE HOUSE, T-184, M.I,D.C.,BHOSARI, PUNE-411 026, INDIA.
5. PATIL DEVIDAS BARKU
EMCURE PHARMACEUTICAL LIMITED EMCURE HOUSE, T-184, M.I,D.C.,BHOSARI, PUNE-411 026, INDIA.
6. MEHTA SAMIT SATISH
EMCURE PHARMACEUTICAL LIMITED EMCURE HOUSE, T-184, M.I,D.C.,BHOSARI, PUNE-411 026, INDIA.

Specification

Documents

Documents
Name Date
1 3339-mum-2010-abstract.pdf 2018-08-10
2 3339-mum-2010-correspondence.pdf 2018-08-10
3 3339-mum-2010-description(provisional).pdf 2018-08-10
4 3339-mum-2010-form 1.pdf 2018-08-10
5 3339-mum-2010-form 2(title page).pdf 2018-08-10
6 3339-mum-2010-form 2.pdf 2018-08-10
7 3339-mum-2010-form 3.pdf 2018-08-10
8 3339-mum-2010-form 5.pdf 2018-08-10
9 3339-MUM-2010-ABSTRACT(28-11-2011).pdf 2011-11-28
10 3339-MUM-2010-CLAIMS(28-11-2011).pdf 2011-11-28
11 3339-MUM-2010-CORRESPONDENCE(28-11-2011).pdf 2011-11-28
12 3339-MUM-2010-DESCRIPTION(COMPLETE)-(28-11-2011).pdf 2011-11-28
13 3339-MUM-2010-FORM 1(28-11-2011).pdf 2011-11-28
14 3339-MUM-2010-FORM 2(28-11-2011).pdf 2011-11-28
15 3339-MUM-2010-FORM 2(TITLE PAGE)-(28-11-2011).pdf 2011-11-28
16 3339-MUM-2010-FORM 3(28-11-2011).pdf 2011-11-28
17 3339-MUM-2010-FORM 5(28-11-2011).pdf 2011-11-28