Patent Information

Application #
Patent Number
Invention Field
CHEMICAL
Publication Type
INA
Publication Number
06/2014
Status
Grant Date
Filing Date
Grant Date
Renewal Date

Abstract

Abstract: Provided herein is an improved, commercially viable and industrially advantageous process for the preparation of a ticagrelor intermediate, (3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][l,3]-dioxol-4-ol, which is useful for preparing ticagrelor or a pharmaceutically acceptable salt thereof in high yield and purity. The present invention further relates to an improved process for the preparation of (lS,4R)-cis-4-acetoxy-2-cyclopenten-l-ol, which is a key starting material in the preparation of the ticagrelor intermediate.

Applicants

1. ACTAVIS GROUP PTC EHF
REYKJAVIKURVEGI 76-78, 220, HAFNARFJOROUR

Inventors

1. KRISHNADATT SHARMA
15, AMARSINGH COMPOUND, R.A. NAGAR, OPP. IIT MAINGATE, POWAI, MUMBAI - 400 076
2. NIKHIL TRIVEDI
601, PARIMAL APARTMENTS, PLOT NO. C-1, SECTOR-23, NERUL, NAVIMUMBAI, PIN-400 706
3. NITIN SHARADCHANDRA PRADHAN
C-602, RUNWAL ESTATE, GHOAD BUNDER ROAD, OPPOSITE LAWKIM COMPANY, MANPADA, THANE (WEST) - 400 601

Specification

1. KRISHNADATT SHARMA
15, AMARSINGH COMPOUND, R.A. NAGAR, OPP. IIT MAINGATE, POWAI, MUMBAI - 400 076
2. NIKHIL TRIVEDI
601, PARIMAL APARTMENTS, PLOT NO. C-1, SECTOR-23, NERUL, NAVIMUMBAI, PIN-400 706
3. NITIN SHARADCHANDRA PRADHAN
C-602, RUNWAL ESTATE, GHOAD BUNDER ROAD, OPPOSITE LAWKIM COMPANY, MANPADA, THANE (WEST) - 400 601

Specification

Documents

Documents
Name Date
1 3332-CHE-2010 DESCRIPTION (COMPLETE) 20-10-2011.pdf 2011-10-20
2 3332-CHE-2010 ABSTRACT 20-10-2011.pdf 2011-10-20
3 3332-CHE-2010 CLAIMS 20-10-2011.pdf 2011-10-20
4 3332-CHE-2010 CORRESPONDENCE OTHERS 20-10-2011.pdf 2011-10-20
5 3332-CHE-2010 DRAWINGS 20-10-2011.pdf 2011-10-20
6 3332-CHE-2010 FORM-2 20-10-2011.pdf 2011-10-20
7 3332-CHE-2010 FORM-5 20-10-2011.pdf 2011-10-20
8 3332-che-2010 correspondence others 09-11-2010.pdf 2010-11-09
9 3332-che-2010 description(provisional) 09-11-2010.pdf 2010-11-09
10 3332-che-2010 form-1 09-11-2010.pdf 2010-11-09
11 3332-che-2010 form-2 09-11-2010.pdf 2010-11-09
12 3332-che-2010 form-3 09-11-2010.pdf 2010-11-09