Patent Information
Application #
Patent Number
Invention Field
CHEMICAL
Publication Type
INA
Publication Number
34/2020
Status
Grant Date
archana@anandandanand.com
Filing Date
Grant Date
Renewal Date
Abstract
Abstract: The present invention provides compounds of Formula (I) or stereoisomers, tautomers, or pharmaceutically acceptable salts or solvates thereof, wherein all the variables are as defined herein. These compounds modulate the activity of farnesoid X receptor (FXR), for example, as agonists. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating a disease, disorder, or condition associated with FXR dysregulation, such as pathological fibrosis, transplant rejection, cancer, osteoporosis, and inflammatory disorders, by using the compounds and pharmaceutical compositions.
Applicants
1. BRISTOL-MYERS SQUIBB COMPANY
Route 206 and Province Line Road
Princeton, New Jersey 08543
Inventors
1. YOON, David S.
c/o Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, New Jersey 08543
2. ANUMULA, Rushith Kumar
c/o Syngene International Limited, Biocon Special Economic Zone
Biocon Park, Plot No. 2 & 3, Bommasandra Industrial Area IV Phase
Jigani Link Road, Bommasandra, Bangalore 560 099
Karnataka
3. CHERUKU, Srinivas
c/o Syngene International Limited, Biocon Special Economic Zone
Biocon Park, Plot No. 2 & 3, Bommasandra Industrial Area IV Phase
Jigani Link Road, Bommasandra, Bangalore 560 099
Karnataka
4. HUANG, Yanting
c/o Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, New Jersey 08543
5. JURICA, Elizabeth Anne
c/o Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, New Jersey 08543
6. MENG, Wei
c/o Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, New Jersey 08543
7. NARA, Susheel Jethanand
c/o Syngene International Limited, Biocon Special Economic Zone
Biocon Park, Plot No. 2 & 3, Bommasandra Industrial Area IV Phase
Jigani Link Road, Bommasandra, Bangalore 560 099
Karnataka
8. NARAYAN, Rishikesh
c/o Goa Engineering College (GEC) Campus
Farmagudi Ponda 403401
Goa
9. SISTLA, Ramesh Kumar
c/o Syngene International Limited, Biocon Special Economic Zone
Biocon Park, Plot No. 2 & 3, Bommasandra Industrial Area IV Phase
Jigani Link Road, Bommasandra, Bangalore 560 099
Karnataka
10. WU, Ximao
c/o Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, New Jersey 08543
11. ZHAO, Guohua
c/o Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, New Jersey 08543
Specification
1. YOON, David S.
c/o Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, New Jersey 08543
2. ANUMULA, Rushith Kumar
c/o Syngene International Limited, Biocon Special Economic Zone
Biocon Park, Plot No. 2 & 3, Bommasandra Industrial Area IV Phase
Jigani Link Road, Bommasandra, Bangalore 560 099
Karnataka
3. CHERUKU, Srinivas
c/o Syngene International Limited, Biocon Special Economic Zone
Biocon Park, Plot No. 2 & 3, Bommasandra Industrial Area IV Phase
Jigani Link Road, Bommasandra, Bangalore 560 099
Karnataka
4. HUANG, Yanting
c/o Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, New Jersey 08543
5. JURICA, Elizabeth Anne
c/o Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, New Jersey 08543
6. MENG, Wei
c/o Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, New Jersey 08543
7. NARA, Susheel Jethanand
c/o Syngene International Limited, Biocon Special Economic Zone
Biocon Park, Plot No. 2 & 3, Bommasandra Industrial Area IV Phase
Jigani Link Road, Bommasandra, Bangalore 560 099
Karnataka
8. NARAYAN, Rishikesh
c/o Goa Engineering College (GEC) Campus
Farmagudi Ponda 403401
Goa
9. SISTLA, Ramesh Kumar
c/o Syngene International Limited, Biocon Special Economic Zone
Biocon Park, Plot No. 2 & 3, Bommasandra Industrial Area IV Phase
Jigani Link Road, Bommasandra, Bangalore 560 099
Karnataka
10. WU, Ximao
c/o Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, New Jersey 08543
11. ZHAO, Guohua
c/o Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, New Jersey 08543
Specification
Documents
Documents
| Name | Date | |
|---|---|---|
| 1 | 202017022199-AbandonedLetter.pdf | 2024-02-19 |
| 2 | 202017022199-Correspondence-230522.pdf | 2022-05-30 |
| 3 | 202017022199-Others-230522.pdf | 2022-05-30 |
| 4 | 202017022199-Proof of Right [09-05-2022(online)].pdf | 2022-05-09 |
| 5 | 202017022199-FER.pdf | 2022-01-18 |
| 6 | 202017022199.pdf | 2021-10-19 |
| 7 | 202017022199-FORM 18 [07-10-2021(online)].pdf | 2021-10-07 |
| 8 | 202017022199-FORM 3 [23-09-2020(online)].pdf | 2020-09-23 |
| 9 | 202017022199-COMPLETE SPECIFICATION [27-05-2020(online)].pdf | 2020-05-27 |
| 10 | 202017022199-DECLARATION OF INVENTORSHIP (FORM 5) [27-05-2020(online)].pdf | 2020-05-27 |
| 11 | 202017022199-FORM 1 [27-05-2020(online)].pdf | 2020-05-27 |
| 12 | 202017022199-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105) [27-05-2020(online)].pdf | 2020-05-27 |
| 13 | 202017022199-POWER OF AUTHORITY [27-05-2020(online)].pdf | 2020-05-27 |
| 14 | 202017022199-PRIORITY DOCUMENTS [27-05-2020(online)].pdf | 2020-05-27 |
| 15 | 202017022199-PROOF OF RIGHT [27-05-2020(online)].pdf | 2020-05-27 |
| 16 | 202017022199-STATEMENT OF UNDERTAKING (FORM 3) [27-05-2020(online)].pdf | 2020-05-27 |