Abstract:
This invention relates to a pharmaceutical composition useful as antioxident with free radical scavenging activity . This invention particularly relates to berginin as an antioxident with free radical scevenging activity obtained from a new source namely Tinospora cripsa. This invention also relates to a process for the isolation of bergenin from Tinospora crispa, a new source, with new antioxidant and free radical scavenging activity. Particularly this invention relates to a process of isolation of bioactive bergenin, a new antioxidant and free radical scavenger from Tinospora crispa, having the formula 1 accompanying this specification, by extracting powdered stems in a polar solvent like rectified spirit, methanol, in glass percolator or in Soxhlet extractor, removing fatty nonpolar constituents by triturating with hexane, dichloromethane, chloroform or ethyl acetate, to get rich bioactive fraction, on crystallisation with polar solvents furnished bergenin (1).
Applicants
1. COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
RAFI MARG, NEW DELHI-110 001,INDIA.
Inventors
1. RAKESH MAURYA
REGIONAL RESEARCH LABORATORY, CANAL ROAD,JAMMU 180 001 INDIA
2. LILA RAM MANAHAS
REGIONAL RESEARCH LABORATORY, CANAL ROAD,JAMMU 180 001 INDIA
3. SURJEET SINGH
REGIONAL RESEARCH LABORATORY, CANAL ROAD,JAMMU 180 001 INDIA
4. ANAMIKA KHAJURIA
REGIONAL RESEARCH LABORATORY, CANAL ROAD,JAMMU 180 001 INDIA
5. YASHBIR SINGH BEDI
REGIONAL RESEARCH LABORATORY, CANAL ROAD,JAMMU 180 001 INDIA
6. OM PARKASH SURI
REGIONAL RESEARCH LABORATORY, CANAL ROAD,JAMMU 180 001 INDIA
7. GHULAM NABI QAZI
REGIONAL RESEARCH LABORATORY, CANAL ROAD,JAMMU 180 001 INDIA
Specification
1. RAKESH MAURYA
REGIONAL RESEARCH LABORATORY, CANAL ROAD,JAMMU 180 001 INDIA
2. LILA RAM MANAHAS
REGIONAL RESEARCH LABORATORY, CANAL ROAD,JAMMU 180 001 INDIA
3. SURJEET SINGH
REGIONAL RESEARCH LABORATORY, CANAL ROAD,JAMMU 180 001 INDIA
4. ANAMIKA KHAJURIA
REGIONAL RESEARCH LABORATORY, CANAL ROAD,JAMMU 180 001 INDIA
5. YASHBIR SINGH BEDI
REGIONAL RESEARCH LABORATORY, CANAL ROAD,JAMMU 180 001 INDIA
6. OM PARKASH SURI
REGIONAL RESEARCH LABORATORY, CANAL ROAD,JAMMU 180 001 INDIA
7. GHULAM NABI QAZI
REGIONAL RESEARCH LABORATORY, CANAL ROAD,JAMMU 180 001 INDIA