The present invention covers 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamide compounds of general formula (I), in which X, R1, R2, R3, R4 and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of cancer or conditions with dysregulated immune responses or other disorders associated with aberrant AHR signaling, as a sole agent or in combination with other active ingredients.
Application ID | 201917031626 |
Invention Field | CHEMICAL |
Date of Application | 2019-08-05 |
Publication Number | 36/2019 |
Name | Address | Country | Nationality |
---|---|---|---|
BAYER AKTIENGESELLSCHAFT | Kaiser-Wilhelm-Allee 1 51373 Leverkusen | Germany | Germany |
BAYER PHARMA AKTIENGESELLSCHAFT | Müllerstr. 178 13353 Berlin | Germany | Germany |
DEUTSCHES KREBSFORSCHUNGSZENTRUM | Im Neuenheimer Feld 280 69120 Heidelberg | Germany | Germany |
Name | Address | Country | Nationality |
---|---|---|---|
GUTCHER, Ilona | Paul-Robeson-Str. 28 10439 Berlin | Germany | BRITISH ISLES |
RÖHN, Ulrike | Boyenstr. 42 10115 Berlin | Germany | Germany |
SCHMEES, Norbert | Bondickstr. 61 13469 Berlin | Germany | Germany |
ZORN, Ludwig | Osianderweg 45A 13509 Berlin | Germany | Germany |
RÖSE, Lars | Fuchsring 82 13465 Berlin | France | Germany |
BADER, Benjamin | Hillmannstr. 14 13467 Berlin | Germany | Germany |
KOBER, Christina | Am Alten Bahnhof 8 35457 Lollar | Germany | Germany |
CARRETERO, Rafael | Mühlingstr. 6 69121 Heidelberg | Germany | Spain |
STÖCKIGT, Detlef | Clara-Zetkin-Str. 27 14471 Potsdam | Germany | Germany |
IRLBACHER, Horst | Winsstr. 47 10405 Berlin | Germany | Germany |
PLATTEN, Michael | Cambridgestr. 7 69115 Heidelberg | Germany | Germany |
Name | Date |
201917031626-CLAIMS [02-07-2021(online)].pdf | 2021-07-02 |
201917031626-COMPLETE SPECIFICATION [05-08-2019(online)].pdf | 2019-08-05 |
201917031626-Correspondence-260819.pdf | 2019-08-28 |
201917031626-DECLARATION OF INVENTORSHIP (FORM 5) [05-08-2019(online)].pdf | 2019-08-05 |
201917031626-DRAWINGS [05-08-2019(online)].pdf | 2019-08-05 |
201917031626-DRAWING [02-07-2021(online)].pdf | 2021-07-02 |
201917031626-FER.pdf | 2021-10-18 |
201917031626-FER_SER_REPLY [02-07-2021(online)].pdf | 2021-07-02 |
201917031626-FORM-26 [23-08-2019(online)].pdf | 2019-08-23 |
201917031626-FORM 18 [05-02-2021(online)].pdf | 2021-02-05 |
201917031626-FORM 1 [05-08-2019(online)].pdf | 2019-08-05 |
201917031626-FORM 3 [05-02-2021(online)].pdf | 2021-02-05 |
201917031626-FORM 3 [13-05-2020(online)].pdf | 2020-05-13 |
201917031626-FORM 3 [16-05-2020(online)].pdf | 2020-05-16 |
201917031626-PETITION UNDER RULE 137 [02-07-2021(online)].pdf | 2021-07-02 |
201917031626-Power of Attorney-260819.pdf | 2019-08-28 |
201917031626-PRIORITY DOCUMENTS [05-08-2019(online)].pdf | 2019-08-05 |
201917031626-Response to office action [06-12-2021(online)].pdf | 2021-12-06 |
201917031626-SEQUENCE LISTING [05-08-2019(online)].pdf | 2019-08-05 |
201917031626-SEQUENCE LISTING(PDF) [05-08-2019(online)].pdf | 2019-08-05 |
201917031626-STATEMENT OF UNDERTAKING (FORM 3) [05-08-2019(online)].pdf | 2019-08-05 |
201917031626-TRANSLATIOIN OF PRIOIRTY DOCUMENTS ETC. [05-08-2019(online)].pdf | 2019-08-05 |
abstract.jpg | 2019-08-28 |
Applicant | Section | Controller | Decision Date | URL |